谁邀请加入新路线图的发布。Image copyright World Health Organization. https://www.who.int/teams/control-of-neglected-tropical-diseases/ending-ntds-together-towards-2030

Yesterday the World Health Organization launched a new road map to prevent, control, eliminate and eradicate a set of 20 neglected tropical diseases, by 2030. The new road map “结束忽视实现可持续发展目标”是一个广泛的协商过程的高潮，涉及全球各种利益相关者，伴侣和疾病专家。

Thedraft road mapwent through several iterations until finally being submitted to the Seventy-third World Health Assembly in May 2020. Due to the pandemic, the WHA moved to virtual meetings predominantly concerned with Covid-19, and the NTD road map was finally endorsed by the WHA in November 2020. Keen to get stuck into the work as soon as possible, the official launch of the road map was set for the 28^th2021年1月，之前世界NTD日on the 30^thof Jan (see last year’s第一世界NTD日的Bugbitten帖子）。

The burden of Neglected Tropical Diseases and achievements since 2012

Neglected Tropical Diseasesare a diverse set of 20 conditions, caused by parasites, bacteria, viruses, fungi, and toxins, affecting around 1.7 billion people worldwide. Predominantly affecting people living in deprived, underserved, and disenfranchised communities, NTDs succeed through our failure to correct inequities. NTDs both thrive in areas of poverty and strengthen the causal roots of poverty, by stunting child development, robbing productivity, reducing quality of life and causing irreversible damage, disability and stigma.

“Their impact is felt more often than not by the very people who are least equipped to bear the burden of suffering and disability, not to mention the profound social and economic burdens of disease.” Dr Mwelecele Ntuli Malecela, Director, WHO Department of Control of NTDs explains in本文。

Huge progress has been made since the launch of the WHO roadmap for 2020 and the2012 London Declaration组织，政府，研究机构和制药公司承诺共同控制和消除至少10个NTD。如今，大约有5亿人面临NTD的风险，而42个国家至少消除了一个NTD。例如，请阅读有关与一组NTD与土壤传播的蠕虫作斗争所取得的收益，在最近的错误博客中。

Whilst this has come on the back of huge efforts and commitment, the world is experiencing new challenges that have revealed, now more than ever, the devastating impact of inequities in health. To ensure no one is left behind and that we #EndTheNeglect, a new approach is needed.

范式转移以加速进步到可持续发展目标

The open consultative approach by the WHO revealed the need for fundamental shifts in strategies and three crucial shifts underpin the new road map:

1. Accelerate programmatic action;从测量过程转变为测量影响，从而增加问责制，基于证据的程序决策和数据驱动的响应。
2. 加强横切方法；Moving from vertical, top-down programmes to horizontal, cross-cutting programming – combining efforts and involving people and partners across sectors and disciplines to build integrated, holistic approaches, and importantly使患者处于这些干预措施的中心。
3. Change operating models and culture to facilitate country-ownership;从由合作伙伴领导到国家驱动和国家拥有的编程，这意味着干预措施将反映地面上的需求and will align with the global health agenda.

TheWHONTD Road map 2021-2030设定了以下总体目标：

• reduce by 90% the number of people requiring treatment for NTDs
• 至少有100个国家消除了至少一个NTD
• eradicate two diseases (dracunculiasis and yaws)
• 将与NTD相关的残疾调节年份（DALYS）减少75％

最重要的是，路线图还列出了20个NTD的10个横切目标和疾病特异性目标。路线图的Sustainability Frameworkwas released yesterday with the launch and the WHO are developing the following to accompany and support the road map: a Monitoring and Evaluation Framework and an Investment case; a research and development blueprint and an updated global strategy on water, sanitation and hygiene (WASH) and NTDs.

Innovation and Research

“Focusing on country-driven solutions is critical to achieving the NTD road map 2030 targets. Investing in developing new tools & innovations in the delivery of NTD related services can help us#endtheneglect&#BeatNTDs” said Dr Katey Owen, Director of NTDs at the Bill and Melinda Gates Foundation, giving the example of onchocerciasis “We still don’t have a drug for the adult worms of this ancient disease, onchocerciasis, or a better diagnostic than the archaic skin-snip.”

昨天的发布强调了研究和创新的关键角色，以弥合我们现在的位置与我们想要到2030年之间的差距（Check out this special issue on NTDs）。Key research areas raised in the road map and in the launch are:

• 这些NTD的流行病学和病理学以及疾病和干预如何与更广泛的社会，环境和人口统计背景相互作用
• Social-anthropological research to move to a patient-centred approach and improve NTD interventions
• Diagnostics that are accessible in low-resource settings, quality assured and appropriate for disease programme targets (control, elimination, surveillance) and at point-of-need (e.g. useable at community level, in peripheral healthcare services etc)
• Effective and efficient treatment strategies and interventions that prevent and treat NTDs, manage cases and provide rehabilitation and care. These interventions need to use platforms that access the hardest-to-reach
• 通过强大的数据收集，管理和分析来绘制协议以及监视和评估策略，以实现基于证据的决策。
• GIS，卫星成像，人工智能和低成本技术等创新技术的开发和使用
• Cross-sectoral strategies working with the Water, Sanitation and Hygiene Sector; One Health approach for human and veterinary disease elimination, vector management and environmental health; a thorough understanding of the impact of climate change on NTDs and NTD services to sustain the gains made

“寻找催化剂来改善南南和南北的合作……我们需要一种综合方法来克服语言，地理和疾病的多年生障碍”。约翰·阿穆西（John Amuasi）博士非洲NTD的非洲研究网络

增强流行国家内部和各个地方的研究能力对于达到NTD 2030路线图目标至关重要。约翰·阿穆西（John Amuasi）博士非洲NTD的非洲研究网络强调了为建立强大的非洲研究能力所做的关键工作。Amuasi博士还强调了必须了解Covid-19-19的影响在生物医学一级和公共卫生层面上对NTD的影响。“我们需要寻求更多地了解Covid-19对NTD的影响，无论是对受NTD影响的人们和未来计划行动的影响。这种知识对于NTD路线图的成功至关重要。”

A particular inspiring statement was given by Gerald Chirinda, founder of未来的非洲论坛andYouth Combating NTDs。“年轻人创新者”他说described how youth groups, and early career researchers & professionals are working on a variety of innovations from local language information sharing using mobiles, last mile delivery of health products and services, and innovative diagnostics, to drive change in their communities.

The road map is now launched. It is is a guide, a vision and a call to action, to end the neglect and beat NTDs.