Biotechnology for a bio-based economy

On World Environment Day, we look at what biotechnology can do to help reduce our reliance on fossil fuels and move towards a bio-based economy.

Today is UNWorld Environment Day, a day for global citizens to increase awareness of and take action on the environmental issues facing us all. The 2019 theme is to beat air pollution, and in light of recentclimate change protests, it seems that the need for cleaner alternatives to refining and burning fossil fuels has never been more keenly felt.

No carbon left behind

A bio-based economy, that harnesses biotechnology and renewable raw materials to create fuels, chemicals and materials, aims to reduce both the consumption of fossilized carbon and the resulting pollution.

I recently attended theSymposium on Biotechnology for Fuels and Chemicals, where the keynote speaker, Jennifer Holmgren (CEO ofLanzatech)的会议提议定下了基调we should limit our fossil-based carbon budget to the essentials, and that energy can be carbon free. Her company has commercialized microbiological systems to make fuel ethanol and bio-based chemical products from industrial carbon waste streams (e.g. steel mill emissions, which would otherwise be released to the atmosphere). Jennifer’s ideology to conserve and recycle industrial carbon is neatly captured in her motto “no carbon left behind”.

The meeting drew together researchers working to the common aim of converting renewable carbon sources (such as biomass and captured carbon) to fuels and chemicals. This year there was a growing focus on creating novel materials such as bioplastics, which are also in demand for environmental reasons.

Research published inBiotechnology for Biofuelsshares the above aims and recent highlights in the journal include the discovery ofnovel fungal enzymesthat help breakdown biomass for bio-refining as well as theengineering of a strainofCorynebacterium glutamicumthat can produce bio-gasoline, whilst tolerating harsh industrial processing. A naturalmutation in maize, that makes it less recalcitrant to ethanol fermentation, has also attracted considerableinterest.

Hempel et. al (2011)
Granules of bioplastic produced in algae

Micro-organisms are increasingly being metabolically engineered to produce biodegradable plastics. As long ago as 2011, astudyinMicrobial Cell Factoriesshowed how algae could be induced to make granules of polyester within the cell (see image). More recent work in the journal shows how bioplastic precursors can also be produced inyeastandbacteria.

Currently, most bio-product innovation remains at the laboratory scale. Due to the相对较低的cost of crude oil, investors see little reason to commercialize fossil fuel alternatives that will cost more to produce. The new technologies and biobased products that do get to market tend to be non-fuel products that are of high market value, however, the demand and price of these is not guaranteed. One strategy to overcome this, described by Holmgren, is to make the bio-refinery flexible in terms of its product. A production line can be swapped out (whilst using the same basic infra-structure) to make more profitable bioproducts, depending on the current market value.

On World Environment Day, we can reflect that there is an escalating social consciousness of the cost of fossil carbon and its associated waste. The solutions are already here, and we need more political and economic incentives to help us use them.

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