Highlights of the BMC series: June 2018

Effect of hypnosis on prostate cancer patients • Patients' beliefs about osteoarthritis • Association between sleep duration and metabolic syndrome • Two new BMC engineering journals • Early morning smoking and asthma risk • Risk factors for MRSA bacteremia prediction • Possible link between autism and blind cavefish

BMC癌:Does hypnosis improve the quality of life for prostate cancer patients?

Flickr: Karl Birrane

患有前列腺癌或乳腺癌的人会出现症状,例如情绪困扰,疲劳和睡眠困难,从而降低其生活质量。虽然先前的研究已经确定了催眠和其他组干预措施在减少乳腺癌患者中疲劳和情绪困扰方面的好处,但格雷戈伊尔的一项研究等。出版于BMC Cancersought to identify whether these types of interventions would also be beneficial to prostate cancer patients.

The study assessed 25 men with prostate cancer and 68 women with breast cancer before and after a self-hypnosis/self-care group intervention. The researchers then analyzed the impact this group intervention had on the patients’ quality of life, sleep difficulties and fatigue.

有趣的是,这项研究的结果表明,尽管女性乳腺癌组对抑郁症,焦虑和疲劳在内的各种症状产生了积极影响,但男性前列腺癌组报告没有影响。研究人员认为,这可能是由于与前列腺癌组相比,乳腺癌组在干预之前经历了更大的困难和不同的癌症治疗。雄性前列腺癌组也报告了干预前几乎没有遇到困扰,睡眠或疲劳的问题,这可能导致据报道缺乏这些症状的改善。

BMC风湿病:Knee osteoarthritis and patients’ beliefs

达洛的研究等。, 出版于BMC风湿病, investigates the beliefs that patients with knee osteoarthritis have the disease, as well as how these beliefs are formed and the impact they have on participating in activity, self-management and health behavior. Thirteen individuals from New Zealand with knee osteoarthritis were interviewed.

研究发现,患者通常不确定如何解释自己的日常症状以及如何影响下降率。这导致患者认为关节置换是他们唯一可用的有效选择。最终,对膝盖骨关节炎的误解导致对个人参与活动,健康行为和自我管理的负面影响。

The researchers concluded that improving the provision of information to those with knee osteoarthritis may help guide positive health behavior and self-management decisions.

BMC Public Health:Association between sleep duration and metabolic syndrome

代谢综合征由多种疾病组成,例如高血压,腰部周围的多余脂肪和异常胆固醇水平,这些疾病会增加中风,心脏病和糖尿病的风险。先前的研究研究了不同睡眠持续时间与肥胖,高血压和高血糖等各种疾病之间的联系。

In a study published byBMC Public Health,金等人研究了睡眠之间的联系duration and metabolic syndrome in Koreans aged 40-69 years old. This cross-sectional study analyzed the data of over 130,000 individuals from the years 2004-2013. Sleep categories assessed were less than 6 hours, 6 to less than 8 hours, 8 to less than 10 hours and at least 10 hours.

The researchers found that less than 6 hours of sleep a day was associated with metabolic syndrome in men, and elevated waist circumference in men and women. More than 10 hours of sleep was associated with elevated waist circumference, reduced high-density lipoprotein cholesterol, and elevated fasting glucose in women, whereas elevated triglycerides and metabolic syndrome were associated with more than 10 hours sleep in both men and women.

BMC生物医学工程&BMC Chemical Engineering:两个新期刊

Flickr: Office of Naval Research

两本新的BMC期刊于6月开放了提交。BMC生物医学工程will focus on the combination of tools and methods from biology and medicine with mathematics, physical sciences and engineering with the ultimate goal of improving human health.BMC Chemical Engineeringwill encompass the production of, use, transformation, transportation and reuse of chemicals, biochemicals, materials and energy.

Both journals are now open for submissions, and many more journals will soon be launched to expand the scope of the BMC series beyond biology and medicine and into engineering. Both journals are open access and peer reviewed, and neither makes editorial decisions on the basis of the interest of a study or its likely impact. The first articles will be published in November 2018.

BMC Pulmonary Medicine:Earlier smoking after waking and the risk of asthma

Research conducted by Arielle Selya, Sunita Thapa and Guarav Mehta investigated whether smoking within 5 minutes of waking up (an indicator of nicotine dependence) was independently associated with asthma. Outcomes of asthma assessed included lifetime asthma, past-year asthma, and having had an asthma attack in the past year.

研究人员发现,在醒来的5分钟内吸烟与回顾性哮喘的可能性增加了约50%。这也与终生哮喘的可能性增加了4倍。这些发现可用于完善吸烟者哮喘的风险评估。

BMC Infectious Diseases:Screening swabs surpass traditional risk factors as predictors of MRSA bacteremia

MRSA - 通过Wikimedia Commons,Janice Haney Carr,疾病控制与预防中心[公共领域]
对于那些治疗MRSA患者的人的常见困境是,是否根据经验和临床估计(经验疗法)以及使用万古霉素来包括自己的疗法,因为过度使用这种抗生素可能会有不良事件。在发表的论文中BMC Infectious Diseases, Butler-Laporte等。评估基于患者因素和MRSA定殖的分数是否能够预测MRSA感染的风险S. aureusbacteremia, to inform the need for empiric coverage.

研究人员发现,MRSA定植超过所有其他因素,是MRSA感染的唯一可靠和独立的预测指标。进一步的患者疾病或疾病不是MRSA定殖的足够预测指标。研究结果表明,基于患者已知的MRSA定殖状态和局部易感模式的临床方法可能是合适的。

BMC Evolutionary Biology:Possible link between autism and blind cavefish

ltshears [公共领域],维基梅迪亚公共
Blind cavefish exhibit human Autism Spectrum Disorders (ASD)-like symptoms. They exhibit repetitive behavior patterns, rarely sleep or interact with mates, swim continuously and have high levels or cortisol (the stress hormone) in their blood. In a paper published byBMC Evolutionary Biology, Yoshizawa等。used this species as a model to study the genetic mechanisms which underlie ASD.

尽管研究人员不认为人类和鱼之间的行为处于相同的复杂程度,但他们的发现确实表明,这两种物种的行为在进化上都是保守的。该研究调查了山洞和人类之间具有相同进化祖先的基因,并确定了相似性。他们还调查了Cavefish谱系中进化的基因,发现ASD风险基因的发展速度是其他基因组中其他基因速率的两倍。研究得出的结论是,人类和鱼类的进化具有产生类似ASD行为的基本神经网络。

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