Highlights of the BMC-series: April 2014

A history of lions • Genetics of strawberry flavor • Mechanisms of bacterial adherence • Fossil snakefly • Surveillance leads to rabies reduction • Masculinity and marital violence • Lifestyle medicine for depression

BMCWordleEvolutionary Biology:A history of lions

博物馆保存的狮子标本的线粒体DNA,包括灭绝的巴巴里狮子(Panthera Leo Leo) and Iranian lion (p . l . persica),对西非和中非的狮子进行了测序,并分析了跨越狮子历史范围的数据。对现代和灭绝种群的线粒体DNA进行的分析表明,最近从非洲迁移到亚洲的狮子比以前认为的狮子。该论文凸显了目前仅使用粗化同工酶分离的分类基于分类的非洲和亚洲狮子,目前仅有的两个狮子保护单位是非洲和亚洲狮子。然而,DNA序列研究对这种分类进行了质疑,作者提出的结果进一步表明,这种二分法需要修订。

Genomics:草莓风味的遗传学

There is interest surrounding the improvement of the flavor of commercial strawberry varieties. Fruit flavor arises from a combination of sugars, acids and volatile compounds. In this paper, RNAseq and analytical chemistry analysis of the segregating progeny from strawberry cultivars, varying for presence-absence of volatile compounds, identify FaFAD1 as the gene controlling the peach flavor-conferring volatile γ-decalactone. The results presented by the authors demonstrate that gene candidates for strawberry fruit traits may be identified by integrating careful phenotyping and transcriptomic analysis with genetics. Since γ-decalactone is only one of many volatiles that can be analyzed by means of this approach, this study sheds light on the potential for the same dataset to be used to identify candidates for other volatiles.

Microbiology:Mechanisms of bacterial adherence

Autotransporter proteins, the largest known family of virulence factors expressed by Gram-negative bacteria, play a prominent role in a number of processes including invasion, cytotoxicity and survival within eukaryotic cells. BpaC, a novel autotransporter adhesion protein, has been identified in the pathogenic speciesBurkholderia MalleiBurkholderia pseudomallei.已经发现它可以介导病原体对呼吸上皮细胞的依从性,并表达体内during the course of aerosol infection. Continued investigation of BpaC may ultimately result in a greater understanding of the virulence of these organisms and contribute to the development of measures that target autotransporters.

Image of the month

Image of the month- Fossil SnakeflyFossil snakefly,Juroraphidia longicollum,from the Jiulongshan Formation (Middle Jurassic) in Inner Mongolia, China. From “New transitional fossil snakeflies from China illuminate the early evolution of Raphidioptera” Liu et al.BMC Evolutionary Biology2014年,14:84

Infectious Diseases:Surveillance leads to rabies reduction

在1990年代,狂犬病在中国重新出现,数量和地理差异逐渐增加。这导致了2005年引入了一项国家监视计划,以调查狂犬病爆发的各个方面,例如疫苗接种覆盖和社会组成。中国疾病控制中心(CCDC)在国家一级协调了监视。政府采取的措施以及对暴露后预防质量的规定以及对驯养动物的管理和疫苗接种的改善,导致中国狂犬病发病率降低。

Women’s Health:Masculinity and marital violence

在这项研究中,探讨了印度尼西亚爪哇人婚姻中男性和暴力行为的看法。确定了三种不同的男性气质。每个立场都对婚姻内的性别秩序/平等和接受性的接受持有一定的看法。据发现,男人对婚姻内暴力的态度根据他们对男性气质的看法而有所不同,这反过来又受文化和社会适应以及宗教教义的影响。

Psychiatry:Lifestyle medicine for depression

Over the past three decades, the prevalence of depression appears to have increased. There is now compelling evidence regarding the involvement of a range of lifestyle factors in the pathogenesis of depression. In this paper, Prof Michael Berk and colleagues review a variety of lifestyle modifications that may have potential front-line clinical application alongside pharmacotherapies and psychological techniques to better manage depression. The authors discuss the major components of Lifestyle Medicine consisting of evidence-based adoption of a number of factors including physical activity, dietary modification, adequate relaxation and social interaction as well as other potential lifestyle factors such as environmental issues. Though the use of medication and psychological techniques are still encouraged, acknowledgment that lifestyle modification should also be a routine part of treatment and preventative efforts is highlighted.

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