Anopheles funestus (photo by Jame Gathany, in the Public Domain, available on www.vectorbase.org)

Like stowaways in tiny drones with no fixed destination, malaria parasites taken up in a bloodmeal by a mosquito travel where the insects take them. The female mosquitoes, who need the blood to nourish their eggs, follow afeeding cycle：首先休息以消化他们的饭菜，移至水体以产卵，然后寻找下一顿饭。对于某些疟疾寄生虫，未来的血液可能与成功感染新的人类宿主相吻合。

The thousands of movements of individual mosquitoes ultimately shape the pattern of malaria infection in the community. Mosquito movement can also influence the effectiveness of interventions. Insecticide-treated nets have a “community effect”, just living close to people who use them is enough to reduce the risk of malaria infection due the killing effect of the nets. However, how far mosquitoes fly and how this responds to interventions aimed at repelling rather than killing are not well known.

Measuring the distances travelled by mosquitoes is not easy. Mosquito mark-release-recapture can be time-consuming and sampling representatively challenging, and genetic markers may not work well over short distances for well-mixed populations. Consequently datasets which directly address mosquito movement are few. Mosquitoes tend to fly as far as they need to, and so the distances are likely to vary by setting and species. Additional sources of data from different settings would help build up a picture.

潜在的信息来源是空间驱蚊剂的试验。在里面trial这激发了我们的研究，空间驱蚊剂由用化学曲林蛋白处理的线圈组成，然后在晚上被燃烧。主要目的是看看蚊子是否是使用驱虫剂转移到非用户的家庭中的。

In this paper, we investigate whether additional information can be squeezed out of the trials in order to estimate parameters of mosquito movement.

We developed a model which uses information on the relative distribution of mosquitoes caught in the houses in a village under different scenarios: when there was zero coverage and when there were spatial repellents used in some or all of the houses in a village. The method estimates the proportion of mosquitoes repelled, the proportion of those repelled that go to another house and the average distance of movement between houses in a village.

一个关键的问题是该方法是否有效。使用仿真，在试验数据中有足够的信息的情况下，发现估计值是准确的。总体上需要有足够数量的蚊子，排斥足够的比例，并且空间驱虫剂的覆盖范围必须不太低。在没有驱虫剂的情况下，还需要提供有关蚊子总数的信息：这将涉及对当前使用的试验设计的修改。

发现激励试验的蚊子很少被排斥，无法产生准确的估计，但这并不排除未来试验的方法。

We hope that the method can be further validated using field data as it becomes available, and that secondary analyses such as this can help to build up the bigger picture to better inform the design of intervention strategies.