BMC Psychology – How to respond to a pandemic: Keep calm and stay at home?

在一个有趣的分析中，慕尼黑技术大学和剑桥大学的研究人员调查了德国与英国居民对Covid-19的大流行的反应差异。他们的发现（现在在BMC Psychology) highlight a striking discrepancy how responders from both countries rated the impact of the pandemic on their financial situation as well as their personal outlook: While German participants reported a lower impact in terms of loss of work and income, they were less hopeful that the pandemic would end soon compared with British participants.

总的来说,这两个种群显示sy的增加mptoms of mental illnesses, most prominently depression and anxieties, induced or worsened by the pandemic. This alarming increase calls for a better public awareness of mental health and mental illness as well as better access to help in both countries.

德国与英国之间的比较特别有趣，因为两国在经济和文化上都非常相似。但是，两国之间对大流行的最初反应有所不同，德国的锁定比英国早得多，英国已被证明影响了死亡人数的数量。

As the data for this study was collected during the first lockdown in both countries (April/May 2020) it will be interesting to see how the mental health response has changed over the course of the pandemic.

BMC医学伦理– Research integrity, misconduct and consequences

Research ethics is a hot topic not only in the science community but is also garnering wide-spread attention among the public. Especially in recent years, cases of prominent researchers suspected of misconduct have been highly publicised across news outlets.

In a recent study published inBMC医学伦理，来自匈牙利，爱尔兰，英国和挪威的研究人员收集并分析了有关科学期刊可用的研究不当行为案例的数据。有趣的是，发现自然科学领域（41.5％）与该领域的出版物数量有关，其次是健康和医学科学（25.1％）和工程学（22％）。

最普遍的不当行为类别是与相关法律不遵守的数据制造和伪造数据，例如知情同意和伦理批准排名第二。此外，研究人员评估了研究不当行为的后果，发现纸质撤回（45.4％），并将资金申请排除在外（35.5％）是最常见的制裁。

这项研究的作者进一步批评了撤回通知通常不包含足够的细节，从而阻碍了缩回过程的透明度。诸如本研究之类的全面分析指导研究社区，以寻找防止不当行为和维护研究完整性标准的方法。

BMC医学研究方法– Equity in clinical trial registration – Why are places of higher disease prevalence not (yet) aligned with trial locations?

旨在调查特定疾病的治疗方案的临床试验通常不会从各自患病率的人群中招募。

This geographical mismatch affects both the quality of care and the validity or generalisability of results and funding bodies are working towards a more equal distribution. Researchers and funding bodies are becoming increasingly aware of these issues, prompting researchers from the University of Oxford to investigate why this mismatch exists and how chief investigators (CIs) of clinical trials can be supported to achieve a more equitable distribution.

The results of their qualitative study have now been published inBMC医学研究方法揭示CIS选择现场选择的主要因素是确保成功的试验程序以及选择较少的研究活性站点相关的风险。主要是，独联体意识到患者招募和保留率的潜在问题，并关注较不成功的试验对他们的声誉和未来资金机会的影响。这通常会导致CIS选择具有个人联系或与他们过去合作的网站，从而使这种不平等系统永存。

The authors suggest strategies to mitigate these perceived risk factors and incentivise chief investigators to align their research sites with the location of disease prevalence while highlighting the benefits experienced by CIs who have previously ‘broken the mould’.

BMC研究笔记– Reforesting our planet using nitrogen-fixing legumes

Awareness of the importance of the tropical rain forests and forests in general for our global climate has grown over the last few years and forest restoration is crucial in our efforts to prevent a climate crisis.

Reforestation programmes are on the rise, but a main hindrance to restoring a diverse plant life are often depleted soils that have lost nutrients and minerals through monocultural farming.

在这里，巴西研究人员介绍了有关使用不同豆科植物在恢复工作中使用的数据，现在在BMC研究笔记. Nitrogen-fixing legumes are a useful tool to restore soils and offer a good basis for second-generation plants, but the process is often slow.

通过测量用不同施肥方案治疗的重新造林块的生物量生长，研究人员能够在种植园发展的早期阶段表现出对额外受精的基本作用。

这些发现对于决策者制定策略来减轻全球变暖并使用植物的自然固定从我们的大气中获取碳。

BMC Pediatrics – Is Vitamin D and magnesium supplementation a successful treatment for children with ADHD?

Attention-Deficit/Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder leading to learning disabilities or social dysfunction in affected children with symptoms often lasting into adulthood.

Previous research has shown that children with ADHD often have lower serum levels of vitamin D and magnesium, but few studies have been conducted to assess the effect of vitamin D/magnesium supplementation on behavioural issues of children diagnosed with ADHD.

In a study published inBMC PediatricsHemamy and colleagues present data from a randomised, placebo-controlled trial investigating the effect of vitamin D/Mg supplementation on Iranian children with ADHD. Interestingly, the researchers find significant improvement in several behavioural variables including emotional and peer problems, where children in the treatment group scored significantly better than those receiving a placebo.

这项研究为更大的临床试验奠定了基础，该试验研究了维生素D和镁对ADHD儿童行为的影响以及导致潜在的新治疗建议的基本生理机制。